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These areas (upper arms, outer-upper thighs, and belly area) have fewer blood vessels than muscle, which allows nutrients to absorb more slowly and consistently over time

Desikan, R., Hancock, J

It may also occur if, during catheter insertion, the needle punctures through the vein

8, 26 The intensity of pain usually peaks within 24 hours, and flares often continue for 7 10 days if left untreated (complete resolution may take longer in some patients)